Hemoglobin is the oxygen-carrying protein in red blood cells. It rises in parallel with hematocrit on TRT and serves as a complementary safety marker. Elevated hemoglobin above 18 g/dL warrants clinical attention.
While hemoglobin and hematocrit are closely correlated, monitoring both provides a more complete picture of red blood cell status. Some men see disproportionate rises in one versus the other.